You could write the entire history of science in the last 50 years in terms of papers rejected by Science of Nature.
— Paul C. Lauterbur, Nobel prize winner for his original research on magnetic resonance imaging. His seminal paper was rejected by the journal Nature in 1973.  Quoted in  Kevin Davies article “Public Library of Science Opens Its Doors.” (Found via Scott Berkun's The Myths of Innovation , p.54.)